細胞名稱

人乳腺癌細胞MX-1

貨物編碼

BFN60810346

產品規格

T25培養瓶x1

1.5ml凍存管x2

細胞數量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研   2類

培養體系

90%DMEM(不含丙酮酸鈉）+10%FBS+1%三抗

培養溫度

37℃

二氧化碳濃度

5%

簡介

人乳腺癌細胞MX-1取自29歲女性供體，貼壁培養，該細胞源于CLS。

注釋

Part of: GrayJW breast cancer cell line panel.

Characteristics: Established from a tumor xenograft established in atyhmic mice.

Doubling time: 30-35 hours (CLS); 113.83 hours 

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

基因突變

/

HLA信息

Class I

HLA-A        A*11:01,74:01

HLA-B        B*35:01,15:03

HLA-C        C*04:01,02:02

Class II

HLA-DQ        DQB1*05:01,03:09

HLA-DR        DRB1*01:03,11:08

STR信息

Amelogenin        X

CSF1PO        11

D2S1338        19

D3S1358        15

D5S818        12

D7S820        11,12 (CLS)

11 (PubMed=25877200)

D8S1179        11,12,13 (CLS)

11 (PubMed=25877200)

D13S317        11,12 (CLS)

11 (PubMed=25877200)

D16S539        12

D18S51        12,16

D19S433        13,15.2,16.2

D21S11        29,30,31,32 (CLS)

29,32 (PubMed=25877200)

FGA        20

Penta D        6,9,11

Penta E        14

TH01        7,9

TPOX        7,8 (CLS)

8 (PubMed=25877200)

vWA        17,18 (CLS)

17 (PubMed=25877200)

參考文獻

PubMed=24176112; DOI=10.1186/gb-2013-14-10-r110

Daemen A., Griffith O.L., Heiser L.M., Wang N.J., Enache O.M., Sanborn Z., Pepin F., Durinck S., Korkola J.E., Griffith M., Hur J.S., Huh N., Chung J., Cope L., Fackler M.J., Umbricht C., Sukumar S., Seth P., Sukhatme V.P., Jakkula L.R., Lu Y., Mills G.B., Cho R.J., Collisson E.A., van't Veer L.J., Spellman P.T., Gray J.W.

Modeling precision treatment of breast cancer.

Genome Biol. 14:R110.1-R110.14(2013)

PubMed=25960936; DOI=10.4161/21624011.2014.954893

Boegel S., Lower M., Bukur T., Sahin U., Castle J.C.

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines.

OncoImmunology 3:E954893-E954893(2014)

PubMed=25485619; DOI=10.1038/nbt.3080

Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.

A comprehensive transcriptional portrait of human cancer cell lines.

Nat. Biotechnol. 33:306-312(2015)