細胞名稱

人軟骨肉瘤細胞SW1353

貨物編碼

BFN60807455

產品規格

T25培養瓶x1

1.5ml凍存管x2

細胞數量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研        1類

培養體系

DMEM高糖培養基+10%FBS+1%三抗 

培養溫度

37℃

二氧化碳濃度

5%

簡介

人軟骨肉瘤細胞SW1353取自72歲女性供體

注釋

Part of: Cancer Cell Line Encyclopedia (CCLE) project.

Part of: MD Anderson Cell Lines Project.

From: Scott and White Clinic; Temple; USA.

Omics: Deep exome analysis.

Omics: Deep RNAseq analysis.

Omics: DNA methylation analysis.

Omics: Protein expression by reverse-phase protein arrays.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

基因突變

Heterozygous for IDH2 p.Arg172Ser (c.516G>C) (PubMed=22057234; CCLE).

Heterozygous for TP53 p.Val203Leu (c.607G>C) (PubMed=19787792; CCLE).

HLA信息

/

STR信息

Amelogenin        X

CSF1PO        12

D2S1338        19,24

D3S1358        15,18

D5S818        10,11

D7S820        9,11

D8S1179        10,11

D13S317        12,13

D16S539        11,12

D18S51        13,17

D19S433        14

D21S11        30,32.2

FGA        22,23

Penta D        10,11

Penta E        12,14

SE33        19,21

TH01        6,9

TPOX        8,11

vWA        16,17

參考文獻

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Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.

Cancer Discov. 6:727-739(2016)

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Characterization of human cancer cell lines by reverse-phase protein arrays.

Cancer Cell 31:225-239(2017)

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An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3

Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Nature 569:503-508(2019)